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The STEP 1 clinical trial showed that participants began seeing measurable weight reduction within the first 4 to 8 weeks of treatment
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Many patients report feeling more energized within days of their first injection, particularly those who were previously deficient in B12 or B6
While the original 2002 paper in the Journal of Cosmetic Dermatology is referenced throughout current dermatology literature (including Pickart & Margolina, 2018), direct access is available through Wiley Online Library
Studies using rat pinealocytes demonstrated that Epithalon upregulates both arylalkylamine N-acetyltransferase (AANAT) and phosphorylated CREB (pCREB), the rate-limiting enzymes in melatonin synthesis
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